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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcd72c032200e082d97feda1ee3f78dd9c9e20d862380965c7e384679a0248f' 
  AND token = 'b4VgP/H3qHh4zX1CgcHM++b4AWwRBGCu2MeoEvL9psg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}