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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c622de585ac7b4e113259710a6cbb0d6cfbe4100da189251ad164ad50d7140b' 
  AND token = 'FfZtZPSzZ6kxv30DfdV3d5ZBIcubP5KnT3KVfRAiKUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}