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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1edbd3520ce391947be05868bd0a375e623a113bc037008c0c9b9d039ab66103' 
  AND token = 'o0G7RxENxAz49dOMVAMfUT1OzIha6geW6j/NBVqu8W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}