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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2edd8a0c3bcbb96f99e5249b8d63b420e18dccc2a53a242dca22dabf3d1508' 
  AND token = '8ODtKjm1riUdFaWFVJ9Z5wjyNPx/nBk8OmBbjPaydFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}