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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e338b0a518f00e1104bf5abafcd384318dcbe3a31629863cc24ee59732ff8cb' 
  AND token = 'AiSe8wGa/l/bOrzVmMISasXT3gDwp4XbNtyPO12ks9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}