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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e3cfc185a46739324af65c134b1c6c60ddbe421a8a45f9e17b3c23b56130ae' 
  AND token = '4cU2JniCY9dIaC3X8/59CL+cQ+fZT6BbaWyc/04YMFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}