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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '232c6f288a496a5d4523726c2718c91e1aed8a39760b1af2a54f54b5e10bc194' 
  AND token = '64poUYbr4LjnN200tUMpMuLqOKZhrci33fui+qLFGBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}