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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9e50bf558461ca54217a3e4afe56af2de9266e935a94aafbfc960d5b2f0a8f' 
  AND token = 'c5KUdcdqAQbhc0aGGsg9M65nI/vvVGVOchxQLGsJvpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}