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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adcb5a1bb54e35114951f7d9e35992aa4fe3845c73873201a9802c535f460acf' 
  AND token = 'un0nG30U/BR/xUrmXZjeRkwf/s/5/ErJZLiWOBW4kdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}