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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2732b7c4aea97f4784920c26a2c673776dff5612c1e7cdc71fca1e4d9a3bf0d' 
  AND token = 'uPIC/thBkHaCEBJhcxNf1TbMrDQHb3BlzbaDaoorCTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}