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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fbc359880ad6b9ed384db2a8424655f6146b59e1b0c9075ee6a2ce2696fa8d1' 
  AND token = 'eC/zqCaI1/UzoFvIuPPxxArhP7fU7X3fJcodjPxY1Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}