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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0ad9e393376ee7f2465987d59b033972145fcd1c1950cda0e3891a479566ac' 
  AND token = 'ro3DnM/8+YK3wJo0Pj5lJ6gO4MPNlvgJDK26QXvdArY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}