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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa24955463e6bde4c6a64a4003886ef650b19f56c21fc74be3a0e00e5573ad3' 
  AND token = 'MK5XM6v2HEOZ7ncy5POAx3dtLFTxwbQQ6N9UC0VpDRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}