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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1508a30e14a4a34bd3c81fe7e066483902d48a9f4e815284c05bfc43729d1156' 
  AND token = 'CLnpN6udK4Vgr83Fe03tWBmwrJ5LYWyrnyz/Fm6XNlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}