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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8f8f132cfb99962047b3b71411f9a766203b9d3cfd154b05c2fea3efc35b9b' 
  AND token = 'C1WyI7IrfUVPVlb027aO5xBRw+VCYs8SsdRmO5688z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}