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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8365a7e317a6ae0aed84d297b431a0f259ba9442ca625018c887f5c742a3f1' 
  AND token = 'nLqAnDvK+O8pgJ1SHcW4Sr09uLyg7JUUAF5PtXrOAw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}