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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ecdd944d19f9759057ac51b09b70b58b8d1d71bf49d9ece89df227cd2b64e5' 
  AND token = '52r2B/S2GZFrhGSc7a99j2tZcJ2P774wnjvY2BFgOq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}