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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d67e1687e6426fa229b654fef43c2874fbe71f631fef86400f6a93e761d15d' 
  AND token = '8qzU3yeSrh8HJ8VCZ3IQFGanNZMr6sXVsTphSpynRpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}