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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dcdc0190052df9f0735b5b5777a9ed6f4d80fd446d048361be4402df745fe3' 
  AND token = 'FZ+hn8GGdTwybO0Fb3i/hR41pamwAxP9CcvvfzWr3jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}