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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b7f4fa40eafb0e89cb0e39879fee6ff9442bf146f1bf2c17e3d5136a047876' 
  AND token = '/UsIMbbQ090DXOZVEVNKKI2DCLPUhI9GqTJ1X2bXUIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}