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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335053c13af715b6a4a29c6975c0d61ce4c990931b04b71dd8dc518a6312df71' 
  AND token = 'G+lFZ5sM8h42hGnmR5ggl9qIYItRA7ny9o+x/Dfws4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}