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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95e580971cfa1336116bda41af735c5ba61198bdddb472ede040dee55362faa' 
  AND token = 'v6S+/2uK0XpnNSYbiX+0vWEeXAWwuqjSf6HpqCZIVyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}