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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07d9d434d28deb2d99eb9be6e2cb21c24445c253e408fd47d20c1ee6218e737e' 
  AND token = 'kDhj42AmQ9utfsjmKkqyQcb0OZPeKmsE0BJoNcjAnTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}