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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b8ae681e6e6683aa122ad8a08c85a2ef23812cbc640de7a4f325df68c9972f' 
  AND token = 'rtx+ooUJ/UkcQGz3mMPlTiO+xyzFgRlWqZJNU2wyrwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}