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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529c51ee55ec43b3035afa676245099088ef5cdd972ebb84bac4c1d4906edf8f' 
  AND token = 'Ux3eK9jnTi7r1/sSQuw3LelmGpXM9v2OQOAIBizAx7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}