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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4147f428a899455478bf63c0f32b9c9a22449269b1ae766775f9777ada9155c4' 
  AND token = 'TarF9F4jr+of74YTD5gDrfwiw8A9pJUXu8FgQuSQc9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}