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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a718466e5cd747d7b2995d8d7d011f8af937a9f88ea61e69c38fb7a912d1c07' 
  AND token = 'eTJSWHFZ4BqhyCBuJP6Ge43ozTDomKr4jVNaGMA2tr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}