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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db01a32357d99cd5dae4237288e7455f11eae7ef652dfa35d549fdfac490efd' 
  AND token = 'rhFlf4Pm3Uz0g1/K8hBGz+tqsOeuo3oKSVA79xtlJVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}