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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499b170cde14f3e8dcd91613ea4e551ba6a44320601fa0d9abde258906f7184c' 
  AND token = 'ch4j470WU7tfIdEX9Qvb9Yl4+tlHJqQa/7BtYbGitYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}