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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c850eb10ff78bc10bb3c43f960f46d497fcc7e4faee21aa80a8db7a32a7772' 
  AND token = 'fz1HOdN2sZ4LxZ89EHhGVjTqcsJfMOf09myB7dbRNkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}