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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4422dc189d0443ad879edc5abcd0c2b08d72a7a3d2992bf27670776b7e43233d' 
  AND token = 'nfUQPZwiJCpb6AiHEc7xCSfJRMP43iLZTlLRFbSwvso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}