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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9a0f875df75b1d15f9ee74897621d5728f6427b878776366dd6e735a6f7dfb2' 
  AND token = 'pBR46arjP+bsNv4cPLdiYx5r2EmktZney2KMAcF0Vgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}