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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83aafca0bc0dc22eb7bb89f99c0aa38c162144a5be10e3590a164babeaa75dbc' 
  AND token = 'UoDE8lU+lZt1KOIJDfNrJrnwK2koNHhM3ZCp0VPOpJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}