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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29f5d7d3c6d84dc112f9a656e6dac5715145a93bc041509f9ce2a7f08bb3902' 
  AND token = 'VPXZ0CjM5HJd29zXPfcIQQjjCVMb86VWSXFfFvQpNLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}