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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2e405350a39c4e22846c19d1e7f005a3186ce990e02d8a94154cbac572204c' 
  AND token = 'qntjpNojhTeuH3p+yjHQBo0a5Bq0SfDVvGYg2Uw3lOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}