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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5222777c152dc9b58544773581d4854f539b9624cbe9acf7cd4258dd598cdd' 
  AND token = 'Q3c8bWvJ5THpFOepnVj/YhKCHTPIa5gFXOHW/5QPSt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}