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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed69e52b3126faeffc2746a96ff65c4b6c3f4b49b71acfe6df26c4721f3e1f7' 
  AND token = 'oMdlqqGsy42ILfzHHqL1TMsNrrZGQLmi1WLMWY1MJrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}