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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcd2840abe0b7df222c3e88f7a784822221916a061e783638adbc2e4a81fa26' 
  AND token = 'N7epz+SheIIgF6jS090XIXNgP348RJUEqy5/TygruiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}