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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f5051d0c9f806e6da23538f95edaf0600877ce74ac1485887eb1bf5072f94f' 
  AND token = 'x2MLMW6e+DaIDqQTA478EX/Tkf2hntn8+Ve1FCa0S9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}