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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38205d5ab5beacbf4763cd2e1f20e42d8c8cd99e519f43c3a0fbc8d2da47143' 
  AND token = 'yNXehfOU5CY1TICNm/Lu/obWYONnHT6Rg1CuaAiQ76c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}