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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4540bcb42e7a5c6b51ff058fe563b541a99a8d8617af58fe976a6824d1614401' 
  AND token = '6IJx1snUbLYRB4TnFeQ5slih5faNDLYfrtm6Jsw+iYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}