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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88c3fe8226322ae69e6f4c752b6aadff29b690c7297fcb3ac06d629331cc097b' 
  AND token = 'gfSHG8WCOu1JJnvC0btPCDloxJ/Bxjs3tB4bVVB6Y0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}