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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9650e25799f1a858e6503f5d2a5ff74e8f96f51c555f59f9707ca5dd9f6443a0' 
  AND token = '3ghoV5mzLVLeG+PZRa1V6cWU8bXCYEowAKh0S+v+15w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}