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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f588f6e73ac27a0bdcbe0ec2d3429b4b0e2e5df6566ab12c680323e738942c22' 
  AND token = 'ZM9ZqeySif8OTtNDLA4VOpbtjJWqsheulAmNyoDkKxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}