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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a59f5a9deb47be1539b168b4841081f21a2c0efffa413425911fec14d7178d9' 
  AND token = 'p7Mlz/0FicOX7hVVDtx+TImj9EYdRTzFW0m4ofBwKMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}