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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0251ce0154e2519681b6fad237f65f42855ac59bdaef58a8d19f7ece5dc6a88b' 
  AND token = 'bQy5Iap1qsjZi2UsrbfLS/U+BDiRXiPo5twb0C5D7YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}