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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d8b6774b5aa7af922942131b8ea328ff26da3078b8b8c8b2c0930c407d3ebf' 
  AND token = 'sClDZ7r9OB/ocV/Ar3VFB3CpuDpWTrIKN6+Ig5tEP2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}