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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5543bc72a96f4b39df06cb698566c402d98fa24c9b6772b2a24a529bfa68c6a8' 
  AND token = 'xtoublCZHvFpMMXhoaa+/uQtvPGgc5tJhGnP/dJAyu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}