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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27704a4acd5fca0f635161743715c9cfc99aa04e74efa9c8565c37afbc810a8' 
  AND token = 'tTQOkqhxMCGhStd/1UAllVgt4w2FQyUzROaGjHyeGXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}