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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0fe59e220377df1729a3be3f5ccd39598b77ad13329da89e87c621409d509c2' 
  AND token = '/LWQ+SOulX6RfYNFZ+GYyPgjiD/oGMNMblcX40bSGKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}